2-Month or 3-Month Contraceptive Injection? Here’s the Difference
- Samantha Pieterse

- Sep 9, 2025
- 11 min read
Updated: Dec 4, 2025

In South Africa, contraceptive injections are one of the most popular birth control choices, and for good reason. No daily pill, no implant procedure, just a quick jab every few months, and you’re covered. For many women, it’s the perfect balance of practical and low-maintenance.
It doesn’t need an alarm on your phone. Once it’s in, you can go about life, school runs, and late-night bottle feeds without the constant reminder of “Did I take my pill today?”
But like every method, the injection isn’t for everyone. There are two different types in South Africa, the 2-month and the 3-month shot, and while both work well, they each come with their own quirks.
Let’s look at how they work, what to expect, and whether one of them might be your best match.
💊 If you’re comparing with other options, you might also want to read our guide on birth control pills in South Africa.
How the 2- and 3-Month Contraceptive Injections Prevent Pregnancy
The contraceptive injection contains a hormone called progestogen. Once it’s given, the hormone is slowly released into your bloodstream over several weeks, which is why it only needs to be repeated every 2 or 3 months.
It prevents pregnancy in two main ways:
It stops ovulation: your ovaries don’t release an egg, so there’s nothing available for sperm to fertilise.
It thickens the cervical mucus: this makes it very difficult for sperm to move through the cervix into the uterus.
This is the same mechanism used in some hormonal IUDs, like the Mirena®, but with the injection, there’s no device inside your uterus, just a simple shot. For many women, this double action also means lighter or even absent periods after a few injections, though some may notice irregular spotting instead.
When given on schedule, the injection is more than 99% effective, putting it among the most reliable methods of contraception available. Its success depends on timing. Once the hormone levels drop after the 2- or 3-month window, the protection wears off, which is why regular appointments are important.
Unlike pills that need a daily reminder, the injection frees you from the stress of remembering. You simply book your next shot, get it done, and your protection continues.

Choosing Between the 2- and 3-Month Contraceptive Injections
In South Africa, two contraceptive injections are available: the 2-month injection (Nur-Isterate®) and the 3-month injection (Depo-Provera®). Both work in the same way, but they differ in how often you need them, the hormone dose, and how your body might respond.
2-Month vs. 3-Month Contraceptive Injection
2-Month Injection (Nur-Isterate®) | 3-Month Injection (Depo-Provera®) | |
|---|---|---|
How Often | Every 8 weeks (2 months). | Every 12 weeks (3 months)/ |
Hormone Dose | Lower progestogen dose. | Higher progestogen dose. |
Bleeding Patterns | Irregular bleeding or spotting is more common. | Periods often stop altogether after a few injections. |
Return to Fertility | Usually quicker (around 6 months on average). | May take up to 12 months (or longer) after the last injection. |
Convenience | More clinic visits are required. | Fewer visits per year. |
Side Effects | May include irregular bleeding, mood changes, and weight changes. | Similar side effects, but bone density concerns are slightly higher with long-term use. |
Best For | Women wanting shorter-term contraception. | Women looking for long-term, low-maintenance contraception. |
Which Birth Control Injection (2- or 3-Month) Is Right for You?
If you’re planning a pregnancy soon
The 2-month injection (Nur-Isterate®) is often the better fit because fertility usually returns sooner.
If you want the lowest-maintenance option
The 3-month injection (Depo-Provera®) means fewer clinic visits and long-lasting cover.
If you prefer to test out the method
The 2-month shot is a shorter commitment, so you can see how your body responds before deciding long-term.
If you’re a busy mom juggling everything
The 3-month shot is a favourite, because of fewer appointments and often no more periods after a few rounds.
If you’re sensitive to hormone dose
The 2-month injection has a lower hormone level, which may suit some women better.
Both injections are safe and highly effective when given on time. The best choice depends on your goals. Whether that’s convenience, shorter commitment, or future pregnancy plans, a consultation can help match the method to your lifestyle.

Pros of the Contraceptive Injection (Why Women in South Africa Love It)
There’s a reason the contraceptive injection is one of the most widely used birth control methods in South Africa. It combines reliability with convenience, which makes it especially appealing for women at different life stages.
Here are some of the biggest advantages:
✅ No daily pill to remember
Once the injection is given, it works in the background for 2 or 3 months. No alarms on your phone, no rushing to the bathroom with a pill pack, your protection is already in place.
✅ Very private
There’s no packaging or reminders lying around, so nobody has to know unless you want to tell them. This makes it a discreet option for women who prefer privacy around their contraceptive choices.
✅ Safe while breastfeeding
Both the 2-month (Nur-Isterate®) and 3-month (Depo-Provera®) injections are considered safe to use while breastfeeding. In fact, they’re commonly recommended for new moms who want effective contraception without interfering with milk supply.
✅ Affordable and widely available
Contraceptive injections are accessible at most public clinics in South Africa, as well as at private practices and pharmacies with nurse services. This makes it one of the easiest methods to start and continue.
✅ Highly effective
When given on schedule, the injection is more than 99% effective, putting it on par with implants and IUDs in terms of reliability.
✅ Periods may become lighter or stop
Many women find that their bleeding reduces over time. For some, periods stop completely, which can be a welcome relief if you’ve struggled with heavy or painful cycles. But, if you’re worried about irregular bleeding on contraception, we’ve written a full guide on spotting and breakthrough bleeding to help you know what’s normal.
Overall, the contraceptive injection ticks a lot of boxes for women who want something simple, private, and reliable. It’s easy to see why it’s such a popular choice in South Africa.
Cons of the Contraceptive Injection (Things to Consider)
Like any form of birth control, the contraceptive injection has its downsides. It’s still a safe and effective method, but it’s important to know what to expect so you’re not caught off guard.
Here are some of the most common drawbacks:
❌ Irregular bleeding
Spotting between periods, unpredictable cycles, or longer gaps without bleeding are very common in the first few months. For some women, periods stop altogether after a few injections, while others may find the irregularity frustrating.
❌ Possible side effects
Some women notice headaches, mood changes, or weight gain while on the injection. These don’t happen to everyone, and many settle after a few cycles, but it’s worth keeping in mind if you’ve struggled with hormone sensitivity before.
❌ Fertility may take longer to return
After stopping the injection, it can take up to a year before your cycles go back to normal. This doesn’t mean you’re permanently infertile, but if you’re planning a pregnancy soon, another method might suit you better.
❌ Bone health with long-term use
With the 3-month injection (Depo-Provera®), there can be a small impact on bone density if used continuously for many years. This isn’t usually a problem in healthy women, but it’s something to be considered if you have risk factors for osteoporosis.
❌ Regular clinic visits required
Unlike a pill pack that can be collected from the pharmacy for months at a time, injections must be given by a nurse on schedule. Missing an appointment means your protection can wear off.
❌ No STI protection
Like most hormonal contraceptives, injections don’t protect against sexually transmitted infections (STIs). Condoms are still recommended if there’s any risk of exposure.
While the cons may look daunting, most women who choose the injection find that the convenience and effectiveness outweigh the downsides. The important thing is knowing what to expect, so you can make an informed choice and book a consult if something doesn’t feel right. If you’re weighing up your options, Mums & Bums offers consultations to help you find the method that matches your lifestyle.
🍼 If short-term contraception is a priority, options like the Copper IUD can be stopped at any time with an immediate return to fertility.

Contraceptive Injection Side Effects and Myths Explained
Like all contraceptives, the injection can come with side effects, but most are temporary, and they don’t mean something is “wrong.” Knowing what’s normal and what’s not can save a lot of unnecessary worry.
Common side effects include:
Irregular bleeding or spotting, especially in the first few months.
Headaches, mood changes, or mild weight gain in some women.
Changes in periods. Some women stop menstruating altogether, which is safe, while others continue with lighter or irregular bleeding.
These effects usually settle over time, and many women continue on the injection without problems. If side effects are bothersome, your nurse or doctor can help you decide whether to continue or switch methods.
Now, let’s clear up some myths that still pop up:
“The injection makes you permanently infertile.”
Not true. Fertility may take a little longer to return after stopping (up to a year for some women), but it does return. The injection has no permanent effect on your ability to have children.
“You’ll definitely gain weight.”
Some women notice changes in appetite or weight, but this isn’t guaranteed. Lifestyle factors often play a bigger role. If you’re worried, your nurse can monitor your weight and discuss options.
“It’s unsafe for your bones.”
Long-term use of the 3-month injection (Depo-Provera®) can affect bone density slightly, but this risk is small in healthy women and improves once you stop. Regular check-ins make it a safe option for most women.
“If your periods stop, it’s dangerous.”
Nope. Having no periods while on the injection is completely safe. The lining of the womb simply doesn’t build up in the same way, which is why bleeding can reduce or stop.
Most side effects of the contraceptive injection are manageable, and the biggest myths don’t hold up when you look at the evidence. With proper medical guidance, it’s a safe, effective, and trusted form of birth control in South Africa.
💊 For more on what to expect with other methods, check out our detailed blog on birth control pills in South Africa.
Contraceptive Injection: Do Your Periods Get Stuck Inside You?
One of the biggest myths we hear in South Africa is that when your periods stop on the contraceptive injection, the blood is somehow “stuck inside” your womb and needs to be released or detoxed. This simply isn’t true.
Here’s what actually happens:
The injection keeps your womb lining very thin.
Because the lining doesn’t build up each month, there’s little or nothing to shed.
That’s why many women notice lighter periods or no bleeding at all.
It’s not because blood is trapped, but because there’s nothing there to come out.
Not having a period on the injection is completely safe. There is no “old blood” building up inside your body. Your womb isn’t storing anything harmful, and your body doesn’t need detox teas, cleanses, or tonics to “flush it out.” The injection simply changes the cycle so the lining doesn’t grow thick enough to bleed, which is medically normal and safe.
Why this myth is dangerous: Some women believe they need to “take a break” from the injection to bring their periods back. Missing or delaying doses, however, can leave you unprotected and increase the risk of an unplanned pregnancy. Staying on schedule is what keeps the injection effective.
Many women even welcome this change, especially if they’ve had heavy or painful periods before. It’s one of the reasons the contraceptive injection is such a popular choice worldwide.
Where to Get the Contraceptive Injection in South Africa
At Mums & Bums in Centurion, we offer both the 2-month (Nur-Isterate®) and 3-month (Depo-Provera®) contraceptive injections. Everything happens in a private setting with a nurse who takes the time to explain how it works, check your health history, and answer your questions.
Many women appreciate being able to combine a quick jab with a full contraception consult. If the injection is the right choice for you, it can usually be given during the same visit. If you’d like to visit us, book online here.
Who Should (and Shouldn’t) Use the Contraceptive Injection?
The contraceptive injection is an excellent fit for women who want something long-lasting and straightforward. It works exceptionally well for busy moms, students, or anyone who struggles to remember a daily pill. Both the 2-month (Nur-Isterate®) and 3-month (Depo-Provera®) injections are safe while breastfeeding, making them a common choice for new mothers. Many women also enjoy that it’s discreet, highly effective, and often leads to lighter or even no periods over time.
On the other hand, it may not suit everyone. If you’re planning a pregnancy soon, the injection can delay the return of fertility for several months after stopping. Women who dislike needles, prefer predictable monthly periods, or have certain health conditions (like severe liver disease or high risk of osteoporosis) may be advised to consider other options. Talking through your health history and future plans with a nurse is the best way to find out if the injection is right for you.

Practical Tips for Using the Contraceptive Injection
💡 Book your next injection before you leave the clinic
This helps you stay on schedule and reduces the risk of missing your window of protection.
💡 Don’t leave it too late
The 2-month shot (Nur-Isterate®) and 3-month shot (Depo-Provera®) both have expiry dates. Once the hormone levels drop, your protection wears off, so timing matters.
💡 Switching from another method?
Ask us how to transition safely from the pill, implant, or IUD so you’re covered throughout.
💡 Track your dates on your phone
A calendar reminder or app can save you from that “Wait… when was my last injection?”
💡 Check in if you notice changes
Irregular bleeding is common, but if side effects are worrying, a quick consult can help you decide if the injection is still right for you.
The Bottom Line: Is the Contraceptive Injection Right for You?
The contraceptive injection is safe, effective, and popular in South Africa for a reason. It takes the pressure off daily pill-taking, offers long-lasting protection, and works well for many women at different life stages. But like all contraceptives, you need to find the method that fits you and your plans.
Still unsure about the birth control injection?
Book your contraception consult here. At Mums & Bums, we’ll walk you through the options and, if the injection is right for you, you can usually have it on the same day.
FAQs on The 2- and 3-Month Birth Control Injection
What’s the difference between the 2-month and 3-month contraceptive injection?
The 2-month injection (Nur-Isterate®) has a lower hormone dose and is given every 8 weeks. The 3-month injection (Depo-Provera®) has a higher dose and lasts 12 weeks. The 2-month version usually gives a quicker return to fertility, while the 3-month shot is more low-maintenance with fewer clinic visits.
Which contraceptive injection is better: 2-month or 3-month?
Neither is “better” for everyone. The 2-month injection suits women who want shorter-term contraception, lighter hormone doses, or plan to fall pregnant in the next year. The 3-month injection suits women who want long-term, low-maintenance protection and don’t mind periods stopping or becoming irregular.
How effective are the 2- and 3-month injections?
Both the 2-month (Nur-Isterate®) and 3-month (Depo-Provera®) injections are more than 99% effective when given on schedule. Protection drops if you miss or delay an injection, because hormone levels fall after the 2- or 3-month window.
Do periods stop on the contraceptive injection?
Yes, they can. Many women on the 3-month injection stop bleeding completely after a few doses because the womb lining stays thin. This is safe, and it does not mean blood is “stuck inside” your body. Some women on the 2-month shot continue to have spotting or irregular cycles instead.
How long does fertility take to return after the injection?
Fertility usually returns faster after the 2-month injection (around 6 months on average). After the 3-month injection, it may take up to 12 months or longer for periods and ovulation to return. Neither injection causes permanent infertility.
What are the side effects of the contraceptive injection?
Common side effects include irregular bleeding, spotting, mood changes, headaches, and mild weight changes. With long-term use of the 3-month injection, there may be a small impact on bone density, which improves once you stop. Side effects are usually temporary and settle over a few months.
Is the contraceptive injection safe while breastfeeding?
Yes. Both the 2-month Nur-Isterate® and 3-month Depo-Provera® injections are considered safe while breastfeeding. They don’t affect milk supply and are commonly recommended for new moms who want reliable contraception.
Where can I get the contraceptive injection in South Africa?
The contraceptive injection is available at public clinics, private practices, pharmacies with nurse services, and reproductive health clinics. In Centurion, Mums & Bums Mother & Baby Clinic offers both the 2-month and 3-month injections with full contraception consultations.



















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